Chmp2b - charged multivesicular body protein 2B

Predicted to enable protein domain specific binding activity. Involved in regulation of modification of postsynaptic structure and regulation of postsynapse organization. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; chromosome 3-linked frontotemporal dementia; and frontotemporal dementia. Orthologous to human CHMP2B (charged multivesicular body protein 2B). [provided by Alliance of Genome Resources, Apr 2022]