Itk - IL2-inducible T-cell kinase

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in several processes, including T cell activation; activation of phospholipase C activity; and antigen receptor-mediated signaling pathway. Predicted to be located in several cellular components, including cell-cell junction; cytosol; and nucleus. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 1. Orthologous to human ITK (IL2 inducible T cell kinase). [provided by Alliance of Genome Resources, Apr 2022]