Ndp - norrin cystine knot growth factor NDP

Predicted to enable cytokine activity; frizzled binding activity; and protein homodimerization activity. Involved in decidualization. Predicted to be located in cell surface; collagen-containing extracellular matrix; and extracellular space. Predicted to be active in extracellular matrix. Human ortholog(s) of this gene implicated in Norrie disease; X-linked exudative vitreoretinopathy 2; and retinopathy of prematurity. Orthologous to human NDP (norrin cystine knot growth factor NDP). [provided by Alliance of Genome Resources, Apr 2022]