Cav2 - caveolin 2

Enables mitogen-activated protein kinase kinase kinase binding activity; phosphoprotein binding activity; and syntaxin binding activity. Involved in several processes, including insulin receptor signaling pathway; negative regulation of endothelial cell proliferation; and positive regulation of peptidyl-tyrosine phosphorylation. Located in several cellular components, including caveola; lipid droplet; and nuclear inner membrane. Part of protein-containing complex. Biomarker of high grade glioma and obesity. Human ortholog(s) of this gene implicated in low tension glaucoma and primary open angle glaucoma. Orthologous to human CAV2 (caveolin 2). [provided by Alliance of Genome Resources, Apr 2022]