Kif1a - kinesin family member 1A

Enables identical protein binding activity and microtubule binding activity. Involved in several processes, including interkinetic nuclear migration; regulation of dendritic spine morphogenesis; and transport along microtubule. Located in several cellular components, including microtubule; neuronal cell body; and secretory vesicle. Is extrinsic component of neuronal dense core vesicle membrane. Part of protein-containing complex. Biomarker of synucleinopathy. Human ortholog(s) of this gene implicated in NESCAV syndrome; hereditary sensory neuropathy; hereditary sensory neuropathy type 2C; hereditary spastic paraplegia; and hereditary spastic paraplegia 30. Orthologous to human KIF1A (kinesin family member 1A). [provided by Alliance of Genome Resources, Apr 2022]