Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cellular response to xenobiotic stimulus; negative regulation of MAPK cascade; and regulation of protein stability. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. Orthologous to human RNF149 (ring finger protein 149). [provided by Alliance of Genome Resources, Apr 2022]