Polr3b - RNA polymerase III subunit B

Predicted to enable DNA binding activity; metal ion binding activity; and ribonucleoside binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in positive regulation of innate immune response and positive regulation of interferon-beta production. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism. Orthologous to human POLR3B (RNA polymerase III subunit B). [provided by Alliance of Genome Resources, Apr 2022]