Cdk2 - cyclin dependent kinase 2

Enables cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Involved in several processes, including cellular response to insulin stimulus; response to cAMP; and response to estradiol. Located in cytosol and nucleus. Used to study membranoproliferative glomerulonephritis. Human ortholog(s) of this gene implicated in prostate cancer and renal cell carcinoma. Orthologous to human CDK2 (cyclin dependent kinase 2). [provided by Alliance of Genome Resources, Apr 2022]