Enables several functions, including Hsp90 protein binding activity; p53 binding activity; and prostaglandin-E synthase activity. Involved in several processes, including negative regulation of cell death; prostaglandin biosynthetic process; and sensory perception of pain. Located in several cellular components, including actin filament; neuronal cell body; and perinuclear region of cytoplasm. Part of protein-containing complex. Orthologous to human PTGES3 (prostaglandin E synthase 3). [provided by Alliance of Genome Resources, Apr 2022]