Vrk1 - VRK serine/threonine kinase 1

Predicted to enable histone kinase activity; nucleosomal histone binding activity; and protein kinase binding activity. Predicted to be involved in Golgi disassembly; histone H3-S10 phosphorylation; and histone H3-T3 phosphorylation. Predicted to act upstream of or within protein autophosphorylation. Predicted to be located in Golgi stack; cytosol; and nuclear lumen. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1A. Orthologous to human VRK1 (VRK serine/threonine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]