Glrx5 - glutaredoxin 5

Predicted to enable glutathione oxidoreductase activity; iron-sulfur cluster binding activity; and metal ion binding activity. Predicted to be involved in [2Fe-2S] cluster assembly; protein maturation by [2Fe-2S] cluster transfer; and protein maturation by [4Fe-4S] cluster transfer. Located in dendrite; neuronal cell body; and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive pyridoxine-refractory sideroblastic anemia 3. Orthologous to human GLRX5 (glutaredoxin 5). [provided by Alliance of Genome Resources, Apr 2022]