Tp73 - tumor protein p73

Enables sequence-specific DNA binding activity. Involved in several processes, including negative regulation of neuron differentiation; positive regulation of MAPK cascade; and positive regulation of oligodendrocyte differentiation. Located in chromatin; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in breast cancer; lung cancer; nephroblastoma; primary ciliary dyskinesia; and renal cell carcinoma. Orthologous to human TP73 (tumor protein p73). [provided by Alliance of Genome Resources, Apr 2022]