Lrp8 - LDL receptor related protein 8

Enables high-density lipoprotein particle binding activity and kinesin binding activity. Involved in several processes, including cellular response to cholesterol; cellular response to growth factor stimulus; and cerebral cortex development. Located in several cellular components, including dendrite; neuronal cell body; and postsynaptic density. Part of microtubule associated complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; dementia; myocardial infarction; and schizophrenia. Orthologous to human LRP8 (LDL receptor related protein 8). [provided by Alliance of Genome Resources, Apr 2022]