Melk - maternal embryonic leucine zipper kinase

Predicted to enable calcium ion binding activity; non-membrane spanning protein tyrosine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including intracellular signal transduction; positive regulation of apoptotic process; and protein autophosphorylation. Predicted to act upstream of or within intrinsic apoptotic signaling pathway in response to oxidative stress. Predicted to be located in cell cortex and plasma membrane. Orthologous to human MELK (maternal embryonic leucine zipper kinase). [provided by Alliance of Genome Resources, Apr 2022]