Irak2 - interleukin-1 receptor-associated kinase 2

Predicted to enable protein heterodimerization activity; protein homodimerization activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including interleukin-1-mediated signaling pathway; regulation of DNA-binding transcription factor activity; and regulation of cytokine-mediated signaling pathway. Predicted to act upstream of or within lipopolysaccharide-mediated signaling pathway and negative regulation of DNA-binding transcription factor activity. Predicted to be located in cytosol. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Orthologous to human IRAK2 (interleukin 1 receptor associated kinase 2). [provided by Alliance of Genome Resources, Apr 2022]