Predicted to enable identical protein binding activity and protein self-association. Predicted to be involved in nuclear membrane organization. Predicted to be located in Golgi apparatus; endoplasmic reticulum lumen; and nuclear inner membrane. Predicted to be integral component of nuclear inner membrane. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy; arrhythmogenic right ventricular dysplasia 5; and autosomal dominant Emery-Dreifuss muscular dystrophy 7. Orthologous to human TMEM43 (transmembrane protein 43). [provided by Alliance of Genome Resources, Apr 2022]