Map1lc3a - microtubule-associated protein 1 light chain 3 alpha

Predicted to enable microtubule binding activity; phosphatidylethanolamine binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including cellular response to amino acid starvation; cellular response to copper ion; and response to morphine. Located in autophagosome membrane; cytosol; and late endosome. Is active in synapse. Biomarker of several diseases, including artery disease (multiple); degenerative disc disease; ischemia (multiple); retinal detachment; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in glioblastoma. Orthologous to human MAP1LC3A (microtubule associated protein 1 light chain 3 alpha). [provided by Alliance of Genome Resources, Apr 2022]