Epb42 - erythrocyte membrane protein band 4.2

Predicted to enable protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in peptide cross-linking. Predicted to act upstream of or within several processes, including hemoglobin metabolic process; iron ion homeostasis; and spleen development. Predicted to be located in cortical cytoskeleton and membrane. Human ortholog(s) of this gene implicated in hereditary spherocytosis and hereditary spherocytosis type 5. Orthologous to human EPB42 (erythrocyte membrane protein band 4.2). [provided by Alliance of Genome Resources, Apr 2022]