Creb3l1 - cAMP responsive element binding protein 3-like 1

Enables transcription cis-regulatory region binding activity. Involved in negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway and positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress. Predicted to be located in several cellular components, including chromatin; endoplasmic reticulum; and nucleus. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 16. Orthologous to human CREB3L1 (cAMP responsive element binding protein 3 like 1). [provided by Alliance of Genome Resources, Apr 2022]