Cir1 - corepressor interacting with RBPJ, 1

Predicted to enable histone deacetylase binding activity; protein kinase binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to act upstream of or within in utero embryonic development and negative regulation of transcription by RNA polymerase II. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Predicted to colocalize with centrosome. Orthologous to human CIR1 (corepressor interacting with RBPJ, CIR1). [provided by Alliance of Genome Resources, Apr 2022]