Cenpe - centromere protein E

Predicted to enable several functions, including kinetochore binding activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Predicted to be involved in several processes, including kinetochore assembly; mitotic sister chromatid segregation; and regulation of mitotic metaphase/anaphase transition. Predicted to act upstream of or within regulation of protein stability and spindle assembly involved in female meiosis I. Predicted to be located in several cellular components, including kinetochore; midbody; and spindle. Predicted to be part of outer kinetochore. Predicted to be active in microtubule. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 13. Orthologous to human CENPE (centromere protein E). [provided by Alliance of Genome Resources, Apr 2022]