Bbs7 - Bardet-Biedl syndrome 7

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in cilium assembly; intracellular transport; and protein localization. Predicted to act upstream of or within several processes, including animal organ development; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and primary palate development. Predicted to be located in centrosome; nucleus; and photoreceptor outer segment. Predicted to be part of BBSome. Predicted to be active in cytoskeleton; membrane; and neuron projection. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome and Bardet-Biedl syndrome 7. Orthologous to human BBS7 (Bardet-Biedl syndrome 7). [provided by Alliance of Genome Resources, Apr 2022]