Ank3 - ankyrin 3

Enables several functions, including cadherin binding activity; spectrin binding activity; and transmembrane transporter binding activity. Involved in several processes, including clustering of voltage-gated sodium channels; positive regulation of protein targeting to membrane; and regulation of ion transport. Located in several cellular components, including Z disc; main axon; and spectrin-associated cytoskeleton. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human ANK3 (ankyrin 3). [provided by Alliance of Genome Resources, Apr 2022]