Rnls - renalase, FAD-dependent amine oxidase

Predicted to enable several functions, including NADH binding activity; epinephrine binding activity; and monoamine oxidase activity. Involved in response to epinephrine; response to ischemia; and response to salt. Located in extracellular space. Biomarker of chronic kidney disease; congestive heart failure; glomerulosclerosis; and interstitial nephritis. Human ortholog(s) of this gene implicated in essential hypertension and hypertension. Orthologous to human RNLS (renalase, FAD dependent amine oxidase). [provided by Alliance of Genome Resources, Apr 2022]