Kdm2a - lysine demethylase 2A

Predicted to enable several functions, including histone H3-methyl-lysine-36 demethylase activity; unmethylated CpG binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including double-strand break repair via nonhomologous end joining; protein demethylation; and regulation of gene expression. Predicted to act upstream of or within several processes, including chordate embryonic development; heart looping; and positive regulation of macromolecule metabolic process. Predicted to be located in chromatin and nucleoplasm. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human KDM2A (lysine demethylase 2A). [provided by Alliance of Genome Resources, Apr 2022]