Kmt5b - lysine methyltransferase 5B

Predicted to enable S-adenosyl-L-methionine binding activity; chromatin binding activity; and histone methyltransferase activity (H4-K20 specific). Predicted to be involved in DNA repair; histone H4-K20 trimethylation; and positive regulation of DNA metabolic process. Predicted to act upstream of or within histone methylation. Predicted to be located in condensed chromosome, centromeric region and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 51. Orthologous to human KMT5B (lysine methyltransferase 5B). [provided by Alliance of Genome Resources, Apr 2022]