Plekha1 - pleckstrin homology domain containing A1

Predicted to enable PDZ domain binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in several processes, including B cell receptor signaling pathway; negative regulation of protein kinase B signaling; and phosphatidylinositol 3-kinase signaling. Predicted to act upstream of or within several processes, including cellular hormone metabolic process; face morphogenesis; and gonad development. Predicted to be located in cytosol; nucleoplasm; and ruffle membrane. Predicted to be active in cytoplasm and membrane. Orthologous to human PLEKHA1 (pleckstrin homology domain containing A1). [provided by Alliance of Genome Resources, Apr 2022]