Predicted to enable ATP binding activity; formate-tetrahydrofolate ligase activity; and protein homodimerization activity. Predicted to be involved in chordate embryonic development; formate metabolic process; and tetrahydrofolate metabolic process. Predicted to be active in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human MTHFD1L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like). [provided by Alliance of Genome Resources, Apr 2022]