Brd7 - bromodomain containing 7

Predicted to enable several functions, including lysine-acetylated histone binding activity; p53 binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; positive regulation of histone acetylation; and regulation of transcription, DNA-templated. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human BRD7 (bromodomain containing 7). [provided by Alliance of Genome Resources, Apr 2022]