Large1 - LARGE xylosyl- and glucuronyltransferase 1

Predicted to enable glucuronosyltransferase activity; manganese ion binding activity; and xylosyltransferase activity. Predicted to be involved in several processes, including muscle cell cellular homeostasis; protein O-linked mannosylation; and skeletal muscle organ development. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A6 and muscular dystrophy-dystroglycanopathy type B6. Orthologous to human LARGE1 (LARGE xylosyl- and glucuronyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]