Marchf1 - membrane associated ring-CH-type finger 1

Predicted to enable MHC protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class II; immune response; and protein polyubiquitination. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; lysosomal membrane; and trans-Golgi network membrane. Predicted to be active in early endosome membrane; late endosome membrane; and lysosome. Orthologous to human MARCHF1 (membrane associated ring-CH-type finger 1). [provided by Alliance of Genome Resources, Apr 2022]