Predicted to enable chromatin binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including brown fat cell differentiation; defense response to bacterium; and response to cold. Biomarker of glucose intolerance. Orthologous to human PLAC8 (placenta associated 8). [provided by Alliance of Genome Resources, Apr 2022]