Lztr1 - leucine zipper like post translational regulator 1

Predicted to enable small GTPase binding activity. Predicted to be involved in negative regulation of Ras protein signal transduction and protein ubiquitination. Predicted to be located in recycling endosome membrane. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in Noonan syndrome 10; Noonan syndrome 2; and neurilemmomatosis. Orthologous to human LZTR1 (leucine zipper like transcription regulator 1). [provided by Alliance of Genome Resources, Apr 2022]