Tbx1 - T-box transcription factor 1

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including animal organ development; regulation of transcription by RNA polymerase II; and vasculature development. Predicted to act upstream of or within several processes, including hard palate development; otic vesicle morphogenesis; and positive regulation of secondary heart field cardioblast proliferation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in DiGeorge syndrome; tetralogy of Fallot; and velocardiofacial syndrome. Orthologous to human TBX1 (T-box transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]