Ormdl3 - ORMDL sphingolipid biosynthesis regulator 3

Predicted to be involved in cellular sphingolipid homeostasis; ceramide metabolic process; and negative regulation of ceramide biosynthetic process. Predicted to act upstream of or within several processes, including negative regulation of B cell apoptotic process; negative regulation of serine C-palmitoyltransferase activity; and positive regulation of protein localization to nucleus. Predicted to be located in endoplasmic reticulum. Predicted to be part of SPOTS complex. Orthologous to human ORMDL3 (ORMDL sphingolipid biosynthesis regulator 3). [provided by Alliance of Genome Resources, Apr 2022]