Ppp1r1b - protein phosphatase 1, regulatory (inhibitor) subunit 1B

Enables dopamine receptor binding activity. Involved in several processes, including memory; response to cocaine; and response to nicotine. Located in dendritic spine head; dendritic spine neck; and nucleus. Is active in glutamatergic synapse and postsynapse. Used to study mental depression; schizophrenia; status epilepticus; and withdrawal disorder. Biomarker of Huntington's disease. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Orthologous to human PPP1R1B (protein phosphatase 1 regulatory inhibitor subunit 1B). [provided by Alliance of Genome Resources, Apr 2022]