Nlrp1a - NLR family, pyrin domain containing 1A

Enables scaffold protein binding activity. Involved in negative regulation of cellular defense response and positive regulation of pyroptosis. Located in neuronal cell body. Part of protein-containing complex. Human ortholog(s) of this gene implicated in vitiligo. Orthologous to human NLRP1 (NLR family pyrin domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]