Pla2g6 - phospholipase A2 group VI

Enables several functions, including ATP-dependent protein binding activity; calcium-independent phospholipase A2 activity; and palmitoyl-CoA hydrolase activity. Involved in several processes, including cardiolipin acyl-chain remodeling; positive regulation of nitrogen compound metabolic process; and positive regulation of secretion. Located in cytosol and mitochondrion. Biomarker of pleurisy. Human ortholog(s) of this gene implicated in dystonia 12; neuroaxonal dystrophy; and neurodegenerative disease (multiple). Orthologous to human PLA2G6 (phospholipase A2 group VI). [provided by Alliance of Genome Resources, Apr 2022]