Slit2 - slit guidance ligand 2

Enables heparan sulfate proteoglycan binding activity. Involved in several processes, including central nervous system development; negative regulation of inflammatory response; and negative regulation of monocyte chemotaxis. Located in plasma membrane. Biomarker of anti-basement membrane glomerulonephritis. Orthologous to human SLIT2 (slit guidance ligand 2). [provided by Alliance of Genome Resources, Apr 2022]