Spg7 - SPG7 matrix AAA peptidase subunit, paraplegin

Predicted to enable ATP binding activity; peptidase activity; and zinc ion binding activity. Involved in mitochondrial outer membrane permeabilization involved in programmed cell death. Predicted to be located in mitochondrial inner membrane. Predicted to be part of m-AAA complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 7. Orthologous to human SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin). [provided by Alliance of Genome Resources, Apr 2022]