Zbtb16 - zinc finger and BTB domain containing 16

Enables several functions, including DNA-binding transcription factor activity; double-stranded DNA binding activity; and protein C-terminus binding activity. Involved in embryonic limb morphogenesis; ossification involved in bone maturation; and protein localization to nucleus. Located in cytosol; nucleus; and plasma membrane. Used to study caudal regression syndrome and polydactyly. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human ZBTB16 (zinc finger and BTB domain containing 16). [provided by Alliance of Genome Resources, Apr 2022]