Tlr9 - toll-like receptor 9

Enables unmethylated CpG binding activity. Involved in several processes, including cellular response to lipopolysaccharide; male gonad development; and microglial cell activation. Located in plasma membrane. Biomarker of acute necrotizing pancreatitis; mastitis; and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in several diseases, including allergic bronchopulmonary aspergillosis; cystic fibrosis; glomerulonephritis (multiple); hepatitis B; and lung disease (multiple). Orthologous to human TLR9 (toll like receptor 9). [provided by Alliance of Genome Resources, Apr 2022]