Cyp3a44 - cytochrome P450, family 3, subfamily a, polypeptide 44

Predicted to enable several functions, including caffeine oxidase activity; iron ion binding activity; and monooxygenase activity. Predicted to be involved in oxidative demethylation and steroid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4) and CYP3A5 (cytochrome P450 family 3 subfamily A member 5). [provided by Alliance of Genome Resources, Apr 2022]