Frmpd4 - FERM and PDZ domain containing 4

Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in positive regulation of synapse structural plasticity and postsynaptic actin cytoskeleton organization. Predicted to be located in cell projection; cytoskeleton; and synapse. Predicted to be part of protein-containing complex. Predicted to be active in dendritic spine. Is expressed in dorsal root ganglion; facial ganglion; lateral ventricle choroid plexus; metencephalon part of 4th ventricle choroid plexus; and trigeminal ganglion. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 104. Orthologous to human FRMPD4 (FERM and PDZ domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]