Dock1 - dedicator of cytokinesis 1

Predicted to enable SH3 domain binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Acts upstream of or within cell migration and hematopoietic progenitor cell differentiation. Predicted to be located in cytosol and nuclear speck. Predicted to be part of guanyl-nucleotide exchange factor complex. Is expressed in endocardial cushion and midgut vascular element. Used to study DiGeorge syndrome and tetralogy of Fallot. Orthologous to human DOCK1 (dedicator of cytokinesis 1). [provided by Alliance of Genome Resources, Apr 2022]