Pon2 - paraoxonase 2

Predicted to enable arylesterase activity and identical protein binding activity. Predicted to be involved in aromatic compound catabolic process and response to toxic substance. Predicted to be located in several cellular components, including lysosome; mitochondrion; and nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in coronary artery disease; familial hypercholesterolemia; neurodegenerative disease (multiple); type 2 diabetes mellitus; and vascular dementia. Orthologous to human PON2 (paraoxonase 2). [provided by Alliance of Genome Resources, Apr 2022]