Bpi - bactericidal permeablility increasing protein

Predicted to enable lipopolysaccharide binding activity. Predicted to be involved in several processes, including negative regulation of cytokine production; negative regulation of macrophage activation; and response to bacterium. Located in cytoplasm. Human ortholog(s) of this gene implicated in Crohn's disease. Orthologous to human BPI (bactericidal permeability increasing protein). [provided by Alliance of Genome Resources, Apr 2022]