Tnn - tenascin N

Enables identical protein binding activity and integrin binding activity. Involved in several processes, including generation of neurons; negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation; and negative regulation of osteoblast differentiation. Acts upstream of or within axonogenesis and cell-matrix adhesion. Located in several cellular components, including CA3 pyramidal cell dendrite; hippocampal mossy fiber expansion; and neuronal cell body. Is expressed in several structures, including forelimb pre-cartilage condensation; metanephros; palatal shelf; skeleton; and spleen. Orthologous to human TNN (tenascin N). [provided by Alliance of Genome Resources, Apr 2022]