Abi2 - abl interactor 2

Predicted to enable several functions, including SH3 domain binding activity; identical protein binding activity; and ubiquitin protein ligase binding activity. Predicted to contribute to small GTPase binding activity. Involved in lens fiber cell morphogenesis; postsynaptic actin cytoskeleton organization; and regulation of dendritic spine morphogenesis. Acts upstream of or within several processes, including camera-type eye development; dendrite development; and learning or memory. Located in adherens junction; dendrite; and glutamatergic synapse. Is active in dendritic spine and postsynaptic actin cytoskeleton. Is expressed in several structures, including fronto-nasal process; future brain; intestine smooth muscle circular layer; nervous system; and trunk. Orthologous to human ABI2 (abl interactor 2). [provided by Alliance of Genome Resources, Apr 2022]