Mcc - mutated in colorectal cancers

Predicted to be involved in several processes, including negative regulation of canonical Wnt signaling pathway; negative regulation of epithelial cell migration; and negative regulation of epithelial cell proliferation. Predicted to be located in several cellular components, including cytoplasmic ribonucleoprotein granule; cytosol; and nucleoplasm. Is expressed in several structures, including embryo mesenchyme; gut; nervous system; primitive streak; and sensory organ. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human MCC (MCC regulator of WNT signaling pathway). [provided by Alliance of Genome Resources, Apr 2022]